sulfo-Cyanine3 alkyne

Alkynes Click chemistry sulfo-Cyanine3
Cat. # Quantity Price Lead time
A13B0 1 mg $125 in stock
B13B0 5 mg $325 in stock
C13B0 10 mg $470 in stock
D13B0 25 mg $850 in stock
E13B0 50 mg $1490 in stock
F13B0 100 mg $1990 in stock
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A water-soluble alkyne dye for copper-catalyzed click chemistry, an analog of Cy3® alkyne.

sulfo-Cyanine3 is a fluorophore compatible with a wide range of fluorescent scanners, imagers, microscopes, and other instrumentation. It is a bright and photostable dye, which is also easily detected in gels by the naked eye in low amounts (<1 nmol).

sulfo-Cyanine3 alkyne, B13B0
sulfo-Cyanine3 alkyne, B13B0
sulfo-Cyanine3 alkyne, B13B0
Structure of sulfo-Cyanine3.5 NHS ester
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Absorbance and emission spectra of sulfo-Cyanine3

Absorbance and emission spectra of sulfo-Cyanine3

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Cyanine5 maleimide reacts with thiols to give dye labeled conjugates.

sulfo-Cyanine3 maleimide

Water soluble thiol-reactive derivative of sulfo-Cyanine3, a Cy3 analog.

FAM alkyne, 6-isomer

Fluorescein dye alkyne for click chemistry conjugation, pure 6-isomer.

General properties

Appearance: dark red powder
Mass spec M+ increment: 653.2
Molecular weight: 691.90
CAS number: 2055138-87-7 (inner salt); 2055138-88-8 (sodium salt)
Molecular formula: C33H38KN3O7S2
Solubility: soluble in water (0.57 M = 40 g/L), DMSO, DMF
Quality control: NMR 1H, HPLC-MS (95%)
Storage conditions: Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.
MSDS: Download
Product specifications

Spectral properties

Excitation/absorption maximum, nm: 548
ε, L⋅mol−1⋅cm−1: 162000
Emission maximum, nm: 563
Fluorescence quantum yield: 0.1
CF260: 0.03
CF280: 0.06

Product citations

  1. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal Imaging and Pharmacokinetic of Fluorescent Compounds in Zebrafish Eleuthero-Embryos After Different Routes of Administration. Scientific Reports, 2021, 11(1), 12229. doi: 10.1038/s41598-021-91612-6.
  2. Tao, Y.; Xie, J.; Zhong, Q.; Wang, Y.; Zhang, S.; Luo, F.; Wen, F.; Xie, J.; Zhao, J.; Sun, X.; Long, H.; Ma, J.; Zhang, Q.; Long, J.; Fang, X.; Lu, Y.; Li, D.; Li, M.; Zhu, J.; Sun, B.; Li, G.; Diao, J.; Liu, C. A novel partially open state of {SHP}2 points to a "multiple gear" regulation mechanism. Journal of Biological Chemistry, 2021, 296, 100538. doi: 10.1016/j.jbc.2021.100538
  3. Guarin, M.; Ny, A.; De Croze, N.; Maes, J.; Léonard, M.; Annaert, P.; de Witte, P. A. M. Pharmacokinetics in Zebrafish Embryos (ZFE) Following Immersion and Intrayolk Administration: A Fluorescence-Based Analysis. Pharmaceuticals, 2021, 14(6), 576. doi: 10.3390/ph14060576
  4. Guarin, M.; Faelens, R.; Giusti, A.; De Croze, N.; Léonard, M.; Cabooter, D.; Annaert, P.; de Witte, P.; Ny, A. Spatiotemporal imaging and pharmacokinetics of fluorescent compounds in zebrafish eleuthero-embryos after different routes of administration. Scientific Reports, 2021, 11, 12229. doi: 10.1038/s41598-021-91612-6
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Cy® is a trademark of GE Healthcare.
This Product is offered and sold for research purposes only. It has not been tested for safety and efficacy in food, drug, medical device, cosmetic, commercial or any other use. Supply does not express or imply authorization to use for any other purpose, including, without limitation, in vitro diagnostic purposes, in the manufacture of food or pharmaceutical products, in medical devices or in cosmetic products.
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